Tsuyoshi Miyaoka Selected Research

Yi-Gan San

1/2016	Effects of Yokukansan, a Japanese Kampo Medicine for Symptoms Associated Autism Spectrum Disorder.
1/2015	Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, multicenter, double-blind, placebo-controlled trial.
1/2015	Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled trial (a Positive and Negative Syndrome Scale, five-factor analysis).
6/2013	Yokukansan (TJ-54) for irritability associated with pervasive developmental disorder in children and adolescents: a 12-week prospective, open-label study.
5/2013	Yokukansan (TJ-54) for treatment of very-late-onset schizophrenia-like psychosis: an open-label study.
11/2012	Yokukansan (TJ-54) for treatment of pervasive developmental disorder not otherwise specified and Asperger's disorder: a 12-week prospective, open-label study.
1/2011	Yi-gan san for treatment of charles bonnet syndrome (visual hallucination due to vision loss): an open-label study.
1/2009	Yi-gan san as adjunctive therapy for treatment-resistant schizophrenia: an open-label study.
4/2008	Yi-gan san for the treatment of neuroleptic-induced tardive dyskinesia: an open-label study.

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Tsuyoshi Miyaoka Research Topics

Disease

28	Schizophrenia (Dementia Praecox) 01/2020 - 01/2005
8	Hyperbilirubinemia 01/2020 - 01/2005
7	Dementia (Dementias) 01/2015 - 04/2008
6	Treatment-Resistant Schizophrenia 01/2021 - 01/2009
5	Hallucinations (Hallucination) 01/2018 - 06/2009
4	Psychotic Disorders (Schizoaffective Disorder) 01/2017 - 04/2008
3	Neuroinflammatory Diseases 01/2020 - 01/2018
3	Liver Diseases (Liver Disease) 01/2018 - 01/2007
3	Delirium 10/2015 - 12/2012
3	Alzheimer Disease (Alzheimer's Disease) 09/2014 - 09/2007
3	Borderline Personality Disorder (Personality Disorders, Borderline) 01/2011 - 04/2008
2	Nervous System Diseases (Neurological Disorders) 01/2022 - 01/2007
2	Catatonic Schizophrenia 01/2018 - 01/2016
2	Rheumatoid Arthritis 01/2018 - 01/2007
2	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2018 - 01/2010
2	Inflammation (Inflammations) 01/2018 - 01/2017
2	Mental Disorders (Mental Disorder) 01/2016 - 05/2005
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2013 - 10/2008
2	Hemolysis 01/2011 - 01/2007
2	Tardive Dyskinesia 01/2011 - 04/2008
2	Gilbert Disease 11/2005 - 01/2005
1	Kernicterus 01/2022
1	Neonatal Hyperbilirubinemia 01/2022
1	Neurologic Manifestations (Neurological Manifestations) 01/2022
1	Primary Hyperparathyroidism 03/2021
1	Hypercalcemia (Milk Alkali Syndrome) 03/2021
1	Ischemic Stroke 07/2019
1	Parkinson Disease (Parkinson's Disease) 07/2019
1	Periodontitis 07/2019
1	Major Depressive Disorder (Major Depressive Disorders) 09/2018
1	Gliosis 01/2018
1	Disorders of Excessive Somnolence (Hypersomnia) 01/2018
1	Hypersensitivity (Allergy) 01/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2018
1	Neoplasms (Cancer) 01/2018
1	Multiple Sclerosis 01/2018
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2017
1	Psychomotor Agitation (Akathisia) 05/2016
1	Iron Overload 05/2016
1	Ataxia (Dyssynergia) 05/2016
1	Autism Spectrum Disorder 01/2016
1	Dyskinesias (Dyskinesia) 05/2013
1	Cognitive Dysfunction 05/2013
1	Lethargy 11/2012
1	Asperger Syndrome (Asperger's Syndrome) 11/2012
1	Charles Bonnet Syndrome 01/2011
1	Somnambulism (Sleepwalking) 01/2010
1	Amnesia (Dissociative Amnesia) 01/2010
1	Multiple Endocrine Neoplasia Type 2a (MEN 2) 01/2010

Drug/Important Bio-Agent (IBA)

10	Antipsychotic Agents (Antipsychotics)IBA 01/2019 - 01/2007
9	Yi-Gan SanIBA 01/2016 - 04/2008
7	BilirubinIBA 01/2022 - 05/2005
5	Minocycline (Cyclops)FDA LinkGeneric 05/2016 - 01/2007
4	Salivary alpha-AmylasesIBA 01/2018 - 05/2010
3	Antidepressive Agents (Antidepressants)IBA 09/2018 - 01/2009
3	ramelteon (Rozerem)FDA Link 10/2015 - 12/2012
3	Inositol (Myoinositol)IBA 08/2014 - 11/2005
3	N-acetylaspartate (N-acetyl aspartate)IBA 08/2014 - 11/2005
3	Pharmaceutical PreparationsIBA 04/2014 - 01/2009
3	Protons (Proton)IBA 09/2007 - 01/2005
3	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2007 - 05/2003
2	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2018 - 01/2016
2	Aripiprazole (Abilify)FDA Link 01/2018 - 01/2016
2	CytokinesIBA 01/2018 - 01/2009
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2012
2	IronIBA 05/2016 - 03/2005
2	technetium Tc 99m bicisate (Neurolite)FDA Link 02/2016 - 02/2016
2	Tetracycline (Achromycin)FDA LinkGeneric 10/2008 - 01/2007
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2008 - 01/2007
2	Fluvoxamine (Luvox)FDA LinkGeneric 09/2003 - 01/2002
1	KetanserinIBA 01/2022
1	Parathyroid Hormone (Parathormone)IBA 03/2021
1	ninjin'yoeitoIBA 01/2021
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2020
1	Biological ProductsIBA 07/2019
1	ParvalbuminsIBA 07/2019
1	dimemorfan (AT 17)IBA 01/2019
1	suvorexantIBA 01/2018
1	BenzodiazepinesIBA 01/2018
1	LipopolysaccharidesIBA 01/2018
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018
1	CalciumIBA 01/2018
1	Chlorpromazine (Thorazine)FDA Link 01/2018
1	Familial apoceruloplasmin deficiencyIBA 05/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2016
1	8-Hydroxy-2'-DeoxyguanosineIBA 11/2015
1	Excitatory Amino Acid AntagonistsIBA 01/2015
1	Memantine (Namenda)FDA Link 09/2014
1	Donepezil (Aricept)FDA LinkGeneric 09/2014
1	Melatonin Receptors (Melatonin Receptor)IBA 12/2012
1	Hypnotics and Sedatives (Sedatives)IBA 01/2010
1	Serum AlbuminIBA 01/2010
1	Zolpidem (Ambien)FDA LinkGeneric 01/2010
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2010

Therapy/Procedure

10	Therapeutics 09/2018 - 04/2008
1	Oral Hygiene (Dental Hygiene) 07/2019
1	Drug Therapy (Chemotherapy) 01/2018
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2017
1	Kampo Medicine (Kampo) 01/2016